Across TCGA pan-cancer cohorts, KRT90P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KRT90P’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KRT90P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT90P is over-expressed in tumor.
HNSC and LUSC are the cancer types where KRT90P tumor–normal differential expression is most reproducible.