KRT8P9

Across TCGA pan-cancer cohorts, KRT8P9 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of KRT8P9’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where KRT8P9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT8P9 is over-expressed in tumor, although a few such as THCA and READ show the opposite, repressed pattern.

KIRP, LUAD, and BRCA are the cancer types where KRT8P9 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT8P9 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	+0.337	<.001	8	view →
LUAD	All	All	+0.159	.001	8	view →
BRCA	All	II,III,IV	+0.243	<.001	6	view →
LUSC	Male	All	+0.246	<.001	4	view →
CHOL	All	All	+0.225	.002	3	view →
KIRC	Male	All	+0.074	.010	3	view →
STAD	Female	All	+0.472	.021	2	view →
UCEC	All	All	+0.174	.013	2	view →
THCA	All	All	−0.097	.024	2	view →
PRAD	All	All	+0.084	.023	2	view →
READ	Female	All	−0.262	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

KRT8P9–KIRP

Open the KIRP breakdown →