KRT8P7

Across TCGA patient cohorts, KRT8P7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,790 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible KRT8P7-associated GO terms across cancer lineages are Positive regulation of ruffle assembly, Positive regulation of blood-brain barrier permeability, and Apical junction assembly. Each is linked with KRT8P7 in more than 11 cancer types. Because this analysis shows association rather than direction, both KRT8P7-to-partner and partner-to-KRT8P7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of ruffle assembly grouped by KRT8P7-low versus KRT8P7-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT8P7→partner) and Y-score (partner→KRT8P7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of ruffle assembly →	+0.064	+0.312	<.001	<.001	3	12
ESCA	Positive regulation of blood-brain barrier permeability →	+0.142	+0.508	<.001	<.001	3	11
ESCA	Apical junction assembly →	+0.056	+0.270	<.001	<.001	3	11
STAD	Cell differentiation involved in embryonic placenta development →	+0.044	+0.358	<.001	<.001	3	11
ESCA	ERBB3 signaling pathway →	+0.093	+0.352	<.001	<.001	3	11
STAD	Pyrimidine nucleoside triphosphate metabolic process →	+0.053	+0.417	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,790 associations by consensus.

Positive regulation of ruffle assembly by KRT8P7 expression — ESCA

Explore this box plot interactively →