KRT8P50

Across TCGA patient cohorts, KRT8P50 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,417 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible KRT8P50-associated GO terms across cancer lineages are Positive regulation of DNA repair, Regulation of DNA repair, and Spindle organization. Each is linked with KRT8P50 in more than 13 cancer types. Because this analysis shows association rather than direction, both KRT8P50-to-partner and partner-to-KRT8P50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by KRT8P50-low versus KRT8P50-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT8P50→partner) and Y-score (partner→KRT8P50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA repair →	+0.033	+0.030	<.001	<.001	3	14
STAD	Regulation of DNA repair →	+0.037	+0.041	<.001	<.001	3	14
STAD	Spindle organization →	+0.043	+0.040	<.001	<.001	3	14
STAD	Signal transduction in response to DNA damage →	+0.041	+0.038	<.001	<.001	3	12
STAD	Positive regulation of double-strand break repair →	+0.032	+0.031	<.001	<.001	3	12
STAD	Regulation of sphingolipid biosynthetic process →	+0.054	+0.042	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,417 associations by consensus.

Positive regulation of DNA repair by KRT8P50 expression — STAD

Explore this box plot interactively →