KRT8P5

Across TCGA pan-cancer cohorts, KRT8P5 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of KRT8P5’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where KRT8P5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT8P5 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUAD, BRCA, and KIRP are the cancer types where KRT8P5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT8P5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+0.291	<.001	8	view →
BRCA	All	II,III,IV	+0.249	<.001	6	view →
KIRP	All	All	+0.084	.003	5	view →
LUSC	Male	All	+0.152	.019	4	view →
UCEC	All	IV	+0.140	.019	2	view →
CHOL	All	All	+0.104	.012	2	view →
THCA	All	All	−0.048	.022	2	view →
KIRC	All	All	+0.058	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

KRT8P5–LUAD

Open the LUAD breakdown →