KRT8P49

Across TCGA pan-cancer cohorts, KRT8P49 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of KRT8P49’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where KRT8P49 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT8P49 is over-expressed in tumor, although a few such as THCA and LIHC show the opposite, repressed pattern.

STAD, COAD, and LUAD are the cancer types where KRT8P49 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT8P49 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	All	+0.391	.005	7	view →
COAD	All	II,III,IV	+0.361	.012	7	view →
LUAD	Male	II,III,IV	+0.266	<.001	6	view →
BRCA	All	II,III,IV	+0.126	<.001	6	view →
UCEC	All	All	+0.201	.003	4	view →
KICH	Female	II,III,IV	+0.109	.010	4	view →
LUSC	All	All	+0.088	.006	4	view →
PRAD	All	All	+0.388	<.001	2	view →
THCA	Female	All	−0.099	<.001	2	view →
KIRC	Male	All	+0.040	.013	2	view →
KIRP	All	All	+0.071	.015	1	view →
LIHC	Male	III,IV	−0.066	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

KRT8P49–STAD

Open the STAD breakdown →