KRT8P35

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KRT8P35 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated KRT8P35 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher KRT8P35 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRT8P35 expression acts as an unfavorable survival marker, although some lineages such as KIRC and PRAD show a favorable association.

DLBC, MESO, and KIRP are the cancer types where KRT8P35 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
DLBCOSTertileIII,IV0.1750.874.02536view →
MESOOSTertileIII,IV0.4520.702.00725view →
KIRPDFSMedianII,III,IV0.6330.878.00221view →
KIRCDFSQuartileIII,IV0.6850.361.01518view →
PRADDFSMedianAll0.9180.850.01418view →
CESCOSMedianII,III,IV0.8470.669.01714view →
CHOLOSQuartileIII,IV0.1360.829.00812view →
STADDFSMedianIV0.2040.571.01412view →
PAADDFSMedianAll0.2110.363.01612view →
LIHCOSTertileIII,IV0.2910.675.0199view →
COADOSMedianAll0.4850.785.0098view →
ESCAOSTertileAll0.5901.000.0396view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

KRT8P35–DLBC (OS)

Kaplan–Meier survival curve for KRT8P35 RNA-high vs -low samples in DLBC.

Open the DLBC breakdown →

Exploration