KRT8P31

Across TCGA pan-cancer cohorts, KRT8P31 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of KRT8P31’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where KRT8P31 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT8P31 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUAD, BRCA, and KIRP are the cancer types where KRT8P31 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT8P31 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.101	<.001	6	view →
BRCA	Female	All	+0.069	<.001	6	view →
KIRP	All	All	+0.068	.003	4	view →
CHOL	All	All	+0.114	<.001	3	view →
STAD	All	All	+0.210	.032	2	view →
PRAD	All	All	+0.075	.001	2	view →
BLCA	Male	All	+0.071	.046	2	view →
THCA	All	All	−0.041	.013	2	view →
COAD	All	III,IV	+0.278	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

KRT8P31–LUAD

Open the LUAD breakdown →