KRT8P22

Across TCGA pan-cancer cohorts, KRT8P22 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated KRT8P22 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher KRT8P22 RNA is associated with better overall survival. In most high-consensus cancer types, elevated KRT8P22 expression acts as an unfavorable survival marker, although some lineages such as CESC and THCA show a favorable association.

CESC, ACC, and UVM are the cancer types where KRT8P22 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	II,III,IV	0.838	0.397	.006	86	view →
ACC	DFS	Tertile	III,IV	0.046	0.670	.001	36	view →
UVM	DFS	Tertile	All	0.390	0.759	.009	36	view →
ESCA	OS	Median	All	0.647	1.000	.015	26	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
THCA	DFS	Tertile	All	0.949	0.814	.005	18	view →
LIHC	OS	Tertile	II,III,IV	0.261	0.511	.015	12	view →
READ	OS	Median	III,IV	1.000	0.758	.016	10	view →
LUAD	OS	Median	All	0.770	0.847	.010	9	view →
STAD	DFS	Tertile	IV	0.712	0.217	.017	6	view →
PRAD	OS	Median	All	0.934	0.785	.018	6	view →
LUSC	DFS	Median	IV	0.827	0.134	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

KRT8P22–CESC (OS)

Open the CESC breakdown →