KRT8P19

Across TCGA patient cohorts, KRT8P19 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,636 significant associations in total. THCA shows the largest number of these associations.

The most reproducible KRT8P19-associated GO terms across cancer lineages are Negative regulation of fatty acid metabolic process, Positive regulation of ruffle assembly, and Vesicle budding from membrane. Each is linked with KRT8P19 in more than 7 cancer types. Because this analysis shows association rather than direction, both KRT8P19-to-partner and partner-to-KRT8P19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of fatty acid metabolic process grouped by KRT8P19-low versus KRT8P19-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT8P19→partner) and Y-score (partner→KRT8P19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of fatty acid metabolic process →	+0.048	+0.130	.001	<.001	3	8
ESCA	Positive regulation of ruffle assembly →	+0.054	+0.087	<.001	<.001	3	8
UCEC	Vesicle budding from membrane →	+0.017	+0.028	<.001	.003	3	8
STAD	Regulation of meiotic cell cycle →	+0.034	+0.121	<.001	<.001	3	7
STAD	Cell differentiation involved in embryonic placenta development →	+0.030	+0.109	<.001	<.001	3	7
COAD	Regulation of mitochondrion organization →	+0.016	+0.135	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,636 associations by consensus.

Negative regulation of fatty acid metabolic process by KRT8P19 expression — ESCA

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