KRT8P11

Across TCGA patient cohorts, KRT8P11 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,029 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRT8P11-associated GO terms across cancer lineages are tRNA methylation, rRNA metabolic process, and 5S class rRNA transcription by RNA polymerase III. Each is linked with KRT8P11 in more than 16 cancer types. Because this analysis shows association rather than direction, both KRT8P11-to-partner and partner-to-KRT8P11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA methylation grouped by KRT8P11-low versus KRT8P11-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT8P11→partner) and Y-score (partner→KRT8P11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	tRNA methylation →	+0.032	+0.729	<.001	<.001	3	17
STAD	rRNA metabolic process →	+0.040	+0.250	<.001	<.001	3	16
TGCT	5S class rRNA transcription by RNA polymerase III →	+0.058	+0.589	<.001	<.001	3	16
STAD	Transcription by RNA polymerase III →	+0.035	+0.249	<.001	<.001	3	15
STAD	tRNA modification →	+0.036	+0.278	<.001	<.001	3	15
STAD	XMP metabolic process →	+0.050	+0.320	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,029 associations by consensus.

tRNA methylation by KRT8P11 expression — TGCT

Explore this box plot interactively →