KRT84

Across TCGA patient cohorts, KRT84 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,623 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRT84-associated GO terms across cancer lineages are Regulation of odontogenesis, Negative regulation of inflammatory response, and Regulation of leukocyte proliferation. Each is linked with KRT84 in more than 11 cancer types. Because this analysis shows association rather than direction, both KRT84-to-partner and partner-to-KRT84 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of odontogenesis grouped by KRT84-low versus KRT84-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT84→partner) and Y-score (partner→KRT84) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Regulation of odontogenesis →	+0.050	+0.033	<.001	<.001	3	12
STAD	Negative regulation of inflammatory response →	+0.028	+0.053	<.001	<.001	3	12
STAD	Regulation of leukocyte proliferation →	+0.044	+0.055	<.001	.001	3	11
STAD	Positive regulation of cell growth →	+0.036	+0.041	<.001	<.001	3	11
STAD	B cell homeostasis →	+0.044	+0.034	<.001	.001	3	10
STAD	Response to tumor cell →	+0.036	+0.036	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,623 associations by consensus.

Regulation of odontogenesis by KRT84 expression — TGCT

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