KRT84

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRT84 mutation is significantly associated with the RNA expression of many other genes, with 2,387 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT84-associated genes across cancer lineages are MIR4797, RNU6-794P, and MIR3619. Each is linked with KRT84 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT84-to-partner and partner-to-KRT84 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4797 grouped by KRT84-low versus KRT84-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT84→partner) and Y-score (partner→KRT84) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READMIR4797 →+0.819+5.054<.001.00134
BLCARNU6-794P →+0.228+4.492<.001.00534
READMIR3619 →+1.479+4.361<.001.00633
UCECTARS3 →+0.403+2.595.005<.00133
UCECRNU6-1318P →+0.274+2.680<.001.00133
UCECSGTA →+0.511+3.799<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,387 associations by consensus.

MIR4797 by KRT84 expression — READ

Box plot of MIR4797 in KRT84-low vs KRT84-high samples in READ.

Explore this box plot interactively →

Exploration