KRT83

Across TCGA cell cohorts, KRT83 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,475 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT83-associated GO terms across cancer lineages are Small GTPase-mediated signal transduction, Autophagosome membrane docking, and Regulation of ruffle assembly. Each is linked with KRT83 in more than 5 cancer types. Because this analysis shows association rather than direction, both KRT83-to-partner and partner-to-KRT83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Small GTPase-mediated signal transduction grouped by KRT83-low versus KRT83-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT83→partner) and Y-score (partner→KRT83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Small GTPase-mediated signal transduction →	+0.040	+0.441	<.001	.004	3	6
LARGE_INTESTINE	Autophagosome membrane docking →	+0.132	+0.891	<.001	<.001	3	6
LARGE_INTESTINE	Regulation of ruffle assembly →	+0.094	+0.629	<.001	<.001	3	5
OVARY	Positive regulation of protein localization to nucleus →	+0.065	+0.526	<.001	.004	3	5
LUNG_NSCLC_LUAD	L-histidine transport →	+0.110	+0.677	<.001	<.001	3	5
LARGE_INTESTINE	Negative regulation of response to endoplasmic reticulum stress →	+0.077	+0.649	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,475 associations by consensus.

Small GTPase-mediated signal transduction by KRT83 expression — OVARY

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