KRT83

Across TCGA cell cohorts, KRT83 mutation is significantly associated with the RNA expression of many other genes, with 224 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRT83-associated genes across cancer lineages are FTHL17, OR2M4, and OR2H1. Each is linked with KRT83 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT83-to-partner and partner-to-KRT83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTHL17 grouped by KRT83-low versus KRT83-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT83→partner) and Y-score (partner→KRT83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	FTHL17 →	+0.026	+4.029	<.001	.007	3	2
OVARY	OR2M4 →	+0.045	+3.530	.002	.001	3	2
OVARY	OR2H1 →	+0.019	+2.859	<.001	.008	3	2
LUNG_NSCLC_LUAD	ECSIT →	-0.604	-3.548	.001	.001	3	2
LUNG_NSCLC_LUAD	IL22RA2 →	+0.098	+1.992	.002	.009	3	2
KIDNEY	PRDM14 →	+0.006	+5.000	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 224 associations by consensus.

FTHL17 by KRT83 expression — PANCREAS

Explore this box plot interactively →