KRT82

Across TCGA patient cohorts, KRT82 mutation is significantly associated with the RNA expression of many other genes, with 2,664 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT82-associated genes across cancer lineages are MIR181A2, DHX37, and CHAF1A. Each is linked with KRT82 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT82-to-partner and partner-to-KRT82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR181A2 grouped by KRT82-low versus KRT82-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT82→partner) and Y-score (partner→KRT82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR181A2 →	+0.483	+3.916	<.001	.006	3	3
UCEC	DHX37 →	+0.431	+3.223	.003	.009	3	3
UCEC	CHAF1A →	+0.769	+3.021	<.001	<.001	3	3
UCEC	MAMDC4 →	+0.674	+3.716	.001	<.001	3	3
STAD	RNU7-90P →	+0.657	+2.997	.002	.006	3	3
UCEC	DOT1L →	+0.585	+3.716	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,664 associations by consensus.

MIR181A2 by KRT82 expression — HNSC

Explore this box plot interactively →