KRT82

Across TCGA patient cohorts, KRT82 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT82-associated genes across cancer lineages are mTOR_pS2448, Caspase-8, and cIAP. Each is linked with KRT82 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT82-to-partner and partner-to-KRT82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mTOR_pS2448 grouped by KRT82-low versus KRT82-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT82→partner) and Y-score (partner→KRT82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.161	-2.986	.020	.035	3	3
SKCM	Caspase-8 →	-0.153	-3.135	.018	.018	3	2
SKCM	cIAP →	+0.157	+2.000	.017	.031	3	2
UCEC	Ku80 →	+0.293	+2.598	.007	.006	3	2
UCEC	Notch1 →	+0.194	+2.584	.003	.011	3	2
UCEC	Bax →	+0.288	+2.817	.010	.036	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

mTOR_pS2448 by KRT82 expression — UCEC

Explore this box plot interactively →