KRT82

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KRT82 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRT82-associated genes across cancer lineages are OR2T1, TRIM49B, and CFHR2. Each is linked with KRT82 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT82-to-partner and partner-to-KRT82 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2T1 grouped by KRT82-low versus KRT82-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT82→partner) and Y-score (partner→KRT82) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINOR2T1 →+0.008+4.437<.001.00431
BLOOD_LeukemiaTRIM49B →+0.140+4.874<.001.00231
BLOOD_LeukemiaCFHR2 →+0.296+4.539<.001.00731
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR2T1 by KRT82 expression — SKIN

Box plot of OR2T1 in KRT82-low vs KRT82-high samples in SKIN.

Explore this box plot interactively →

Exploration