Across TCGA patient cohorts, KRT81 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,119 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KRT81-associated GO terms across cancer lineages are Negative regulation of cell growth, Wnt protein secretion, and Protein hydroxylation. Each is linked with KRT81 in more than 15 cancer types. Because this analysis shows association rather than direction, both KRT81-to-partner and partner-to-KRT81 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT81→partner) and Y-score (partner→KRT81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Negative regulation of cell growth →	+0.032	+0.440	<.001	<.001	3	16
ESCA	Wnt protein secretion →	+0.088	+0.888	<.001	<.001	3	15
TGCT	Protein hydroxylation →	+0.055	+0.418	<.001	<.001	3	15
ESCA	Collagen fibril organization →	+0.061	+0.711	<.001	.004	2	16
TGCT	Positive regulation of fibroblast proliferation →	+0.046	+0.496	<.001	<.001	3	14
SARC	Respiratory burst involved in defense response →	+0.065	+0.581	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,119 associations by consensus.

Exploration

KRT81 survival (RNA) · tumor vs normal (RNA) · all KRT81 data types