KRT80

Across TCGA pan-cancer cohorts, KRT80 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KRT80 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher KRT80 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KRT80 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

HNSC, UCEC, and CCRCC are the cancer types where KRT80 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	1.000	0.903	.004	27	view →
UCEC	DFS	Quartile	II,III,IV	1.000	0.460	.018	18	view →
CCRCC	OS	Median	IV	0.150	0.785	.040	4	view →
LUAD	DFS	Quartile	III,IV	0.391	0.780	.049	2	view →
PDAC	OS	Tertile	II,III,IV	0.336	0.642	.010	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KRT80–HNSC (DFS)

Open the HNSC breakdown →