Across TCGA patient cohorts, KRT79 mutation is significantly associated with the RNA expression of many other genes, with 1,516 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT79-associated genes across cancer lineages are RNU6-799P, MIR4478, and ACE3P. Each is linked with KRT79 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT79-to-partner and partner-to-KRT79 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT79→partner) and Y-score (partner→KRT79) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-799P →	+0.815	+3.514	<.001	.002	3	3
BLCA	MIR4478 →	+0.318	+4.814	<.001	<.001	3	3
LUSC	ACE3P →	+0.049	+5.005	<.001	.002	3	3
COAD	BPY2DP →	+0.174	+4.824	<.001	.002	3	3
BRCA	MTND5P21 →	+0.060	+4.873	.007	.001	3	2
BRCA	GARS1P1 →	+0.048	+4.298	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,516 associations by consensus.

Exploration

KRT79 survival (RNA) · tumor vs normal (RNA) · all KRT79 data types