Across TCGA patient cohorts, KRT79 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT79-associated genes across cancer lineages are PCNA, PRDX1, and ATM. Each is linked with KRT79 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT79-to-partner and partner-to-KRT79 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT79→partner) and Y-score (partner→KRT79) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.319	+3.584	.002	.002	3	2
UCEC	PRDX1 →	+0.232	+3.169	.019	.019	3	2
UCEC	ATM →	-0.516	-3.584	.018	.002	3	2
UCEC	Caspase-7-cleavedD198 →	+0.943	+2.189	<.001	.034	3	2
UCEC	c-Met_pY1235 →	+0.086	+2.459	.016	.020	3	2
COAD	TIGAR →	+0.477	+2.815	.028	.036	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

KRT79 survival (RNA) · tumor vs normal (RNA) · all KRT79 data types