KRT74

Across TCGA patient cohorts, KRT74 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,388 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KRT74-associated proteins across cancer lineages are KRT5, PKP1, and NIP7. Each is linked with KRT74 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT74-to-partner and partner-to-KRT74 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT74 versus KRT5 in PDAC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT74→partner) and Y-score (partner→KRT74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	KRT5 →	+1.875	+0.089	<.001	.004	3	4
UCEC	PKP1 →	+1.252	+1.203	<.001	<.001	3	4
HNSC	NIP7 →	+0.394	+0.782	<.001	<.001	3	3
BRCA	NOP2 →	+0.435	+0.056	<.001	.003	3	3
LSCC	PDCD11 →	+0.295	+0.574	<.001	<.001	3	3
LSCC	PES1 →	+0.317	+0.562	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,388 associations by consensus.

KRT74 vs KRT5 — PDAC

Explore this scatter interactively →