KRT73-AS1

Across TCGA pan-cancer cohorts, KRT73-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated KRT73-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher KRT73-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT73-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and STAD show a favorable association.

UVM, TGCT, and LIHC are the cancer types where KRT73-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	II,III,IV	0.332	0.773	<.001	69	view →
TGCT	OS	Tertile	II,III,IV	0.670	1.000	.005	36	view →
LIHC	DFS	Tertile	II,III,IV	0.177	0.497	.003	33	view →
KIRC	OS	Median	II,III,IV	0.788	0.681	.014	21	view →
STAD	OS	Median	IV	0.565	0.239	.019	18	view →
LUSC	DFS	Tertile	II,III,IV	0.583	0.331	.004	17	view →
LAML	DFS	Tertile	All	0.563	0.286	.033	14	view →
ESCA	OS	Tertile	III,IV	0.736	0.498	.022	12	view →
UCS	DFS	Tertile	IV	0.323	0.741	.046	12	view →
ACC	OS	Tertile	All	0.208	0.728	.004	12	view →
DLBC	OS	Median	III,IV	0.637	1.000	.018	10	view →
OV	OS	Quartile	III,IV	0.749	0.675	.012	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

KRT73-AS1–UVM (DFS)

Open the UVM breakdown →