KRT72

Across TCGA patient cohorts, KRT72 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT72-associated genes across cancer lineages are Caveolin-1, RAD51, and JNK_pT183_Y185. Each is linked with KRT72 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT72-to-partner and partner-to-KRT72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caveolin-1 grouped by KRT72-low versus KRT72-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT72→partner) and Y-score (partner→KRT72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caveolin-1 →	-0.656	-2.000	.024	.030	3	3
LUAD	RAD51 →	+0.239	+2.824	.022	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.144	-1.893	.033	.016	3	1
UCEC	JNK2 →	+0.238	+2.415	.002	.003	3	1
UCEC	MEK1 →	+0.562	+3.087	<.001	<.001	3	1
UCEC	p62 Lck ligand →	+0.257	+3.321	.049	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Caveolin-1 by KRT72 expression — UCEC

Explore this box plot interactively →