KRT72

Across TCGA cell cohorts, KRT72 RNA expression is significantly associated with the go_rna of many other GO terms, with 354 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRT72-associated GO terms across cancer lineages are Negative regulation of inclusion body assembly, Maintenance of protein location in nucleus, and Negative regulation of tumor necrosis factor superfamily cytokine production. Each is linked with KRT72 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT72-to-partner and partner-to-KRT72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of inclusion body assembly grouped by KRT72-low versus KRT72-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT72→partner) and Y-score (partner→KRT72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of inclusion body assembly →	+0.103	+0.022	.006	.009	3	3
BLOOD_Leukemia	Maintenance of protein location in nucleus →	+0.057	+0.359	<.001	.001	3	3
LUNG_NSCLC_LUAD	Negative regulation of tumor necrosis factor superfamily cytokine production →	+0.054	+0.012	.001	.005	3	3
LUNG_NSCLC_LUAD	Regulation of cell size →	+0.052	+0.010	<.001	.006	3	2
OESOPHAGUS	Negative regulation of 3'-UTR-mediated mRNA stabilization →	+0.150	+0.026	.003	.006	3	2
BREAST	Negative regulation of leukocyte tethering or rolling →	+0.816	+0.025	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 354 associations by consensus.

Negative regulation of inclusion body assembly by KRT72 expression — LARGE_INTESTINE

Explore this box plot interactively →