KRT71

Across TCGA patient cohorts, KRT71 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,014 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRT71-associated GO terms across cancer lineages are Negative regulation of Wnt signaling pathway, Mesenchymal cell differentiation, and Morphogenesis of a branching structure. Each is linked with KRT71 in more than 15 cancer types. Because this analysis shows association rather than direction, both KRT71-to-partner and partner-to-KRT71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of Wnt signaling pathway grouped by KRT71-low versus KRT71-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT71→partner) and Y-score (partner→KRT71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Negative regulation of Wnt signaling pathway →	+0.055	+0.167	<.001	<.001	3	16
TGCT	Mesenchymal cell differentiation →	+0.069	+0.164	<.001	<.001	3	15
TGCT	Morphogenesis of a branching structure →	+0.064	+0.156	<.001	<.001	3	15
TGCT	Mesenchyme morphogenesis →	+0.107	+0.163	<.001	<.001	3	15
STAD	Stem cell differentiation →	+0.058	+0.118	<.001	<.001	3	14
TGCT	Smooth muscle cell differentiation →	+0.072	+0.156	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,014 associations by consensus.

Negative regulation of Wnt signaling pathway by KRT71 expression — TGCT

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