KRT71

Across TCGA patient cohorts, KRT71 mutation is significantly associated with the RNA expression of many other genes, with 1,357 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT71-associated genes across cancer lineages are RNU6-338P, GAS2L1, and ECHS1. Each is linked with KRT71 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT71-to-partner and partner-to-KRT71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-338P grouped by KRT71-low versus KRT71-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT71→partner) and Y-score (partner→KRT71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-338P →	+0.145	+4.142	<.001	.006	3	3
UCEC	GAS2L1 →	+0.577	+2.849	<.001	.001	3	3
UCEC	ECHS1 →	+0.346	+2.170	.009	.009	3	3
LGG	MTHFD2P2 →	+0.179	+7.977	<.001	.007	3	2
UCEC	RNA5SP423 →	+0.523	+2.132	.002	<.001	3	2
BRCA	MIR514B →	+0.278	+7.471	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,357 associations by consensus.

RNU6-338P by KRT71 expression — COAD

Explore this box plot interactively →