KRT71

Across TCGA patient cohorts, KRT71 mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT71-associated genes across cancer lineages are eEF2, ERK2, and Ku80. Each is linked with KRT71 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT71-to-partner and partner-to-KRT71 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by KRT71-low versus KRT71-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT71→partner) and Y-score (partner→KRT71) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.315	+2.999	.021	.035	3	2
UCEC	ERK2 →	+0.227	+2.584	.002	.001	3	2
UCEC	Ku80 →	+0.240	+2.100	.008	.003	3	2
UCEC	Smad3 →	+0.118	+3.321	.041	.010	3	2
UCEC	STAT3_pY705 →	-0.328	-2.105	.001	.017	3	2
UCEC	Caspase-7-cleavedD198 →	+0.814	+2.135	<.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

eEF2 by KRT71 expression — UCEC

Explore this box plot interactively →