KRT7

Across TCGA patient cohorts, KRT7 protein abundance is significantly associated with the RNA expression of many other genes, with 11,381 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KRT7-associated genes across cancer lineages are KRT7-AS, KRT87P, and TACSTD2. Each is linked with KRT7 in more than 6 cancer types. Because this analysis shows association rather than direction, both KRT7-to-partner and partner-to-KRT7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KRT7 versus KRT7-AS in LSCC, with a Pearson correlation of 0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT7→partner) and Y-score (partner→KRT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KRT7-AS →	+2.126	+1.355	<.001	<.001	3	7
LSCC	KRT87P →	+1.081	+1.080	<.001	<.001	3	6
OV	TACSTD2 →	+1.732	+0.798	.002	.001	3	5
LSCC	TSPAN1 →	+2.307	+1.168	<.001	<.001	3	4
BRCA	SLPI →	+2.374	+0.892	.003	.002	3	4
OV	SGO1 →	-0.763	-1.019	.005	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,381 associations by consensus.

KRT7 vs KRT7-AS — LSCC

Explore this scatter interactively →