KRT7

Across TCGA cell cohorts, KRT7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,956 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KRT7-associated GO terms across cancer lineages are Small GTPase-mediated signal transduction, Membrane biogenesis, and Ventricular cardiac muscle cell development. Each is linked with KRT7 in more than 13 cancer types. Because this analysis shows association rather than direction, both KRT7-to-partner and partner-to-KRT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Small GTPase-mediated signal transduction grouped by KRT7-low versus KRT7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT7→partner) and Y-score (partner→KRT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Small GTPase-mediated signal transduction →	+0.053	+1.881	.001	.001	3	14
LIVER	Membrane biogenesis →	+0.122	+5.959	<.001	<.001	3	12
STOMACH	Ventricular cardiac muscle cell development →	+0.259	+4.086	.004	.002	3	12
LIVER	Membrane assembly →	+0.121	+5.564	<.001	<.001	3	12
BONE	Negative regulation of signaling receptor activity →	+0.140	+2.841	<.001	<.001	3	11
LIVER	Regulation of isotype switching to IgE isotypes →	+1.469	+5.152	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,956 associations by consensus.

Small GTPase-mediated signal transduction by KRT7 expression — BONE

Explore this box plot interactively →