KRT7-AS

Across TCGA pan-cancer cohorts, KRT7-AS RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of KRT7-AS’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where KRT7-AS RNA is repressed in tumor relative to normal tissue. In most cancer types KRT7-AS is over-expressed in tumor, although a few such as KIRC and LUSC show the opposite, repressed pattern.

KIRC, COAD, and LUSC are the cancer types where KRT7-AS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT7-AS RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	−0.753	<.001	11	view →
COAD	Female	II,III,IV	+0.404	<.001	10	view →
LUSC	Female	II,III,IV	−2.690	<.001	6	view →
STAD	Male	All	+1.357	<.001	6	view →
BRCA	Female	All	−0.891	<.001	6	view →
HNSC	All	II,III,IV	−0.403	.009	6	view →
CHOL	All	All	+2.808	<.001	3	view →
BLCA	All	IV	+2.645	.007	3	view →
KICH	All	III,IV	−1.254	.013	2	view →
THCA	All	IV	+0.662	.010	2	view →
PRAD	All	All	−0.531	.021	2	view →
READ	Female	All	+0.488	.030	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

KRT7-AS–KIRC

Open the KIRC breakdown →