Across TCGA patient cohorts, KRT5 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,480 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KRT5-associated proteins across cancer lineages are KRT5_S64, KRT17, and KRT5_S50. Each is linked with KRT5 in more than 7 cancer types. Because this analysis shows association rather than direction, both KRT5-to-partner and partner-to-KRT5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT5→partner) and Y-score (partner→KRT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	KRT5_S64 →	+2.899	+3.802	.002	.009	3	8
LSCC	KRT17 →	+1.337	+2.214	<.001	<.001	3	7
PDAC	KRT5_S50 →	+2.222	+2.701	<.001	<.001	3	7
LSCC	KRT5_S571 →	+2.067	+3.252	<.001	<.001	3	7
PDAC	KRT5_S75 →	+2.169	+2.602	<.001	<.001	3	7
UCEC	SERPINB5 →	+1.524	+2.677	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,480 associations by consensus.

Exploration

KRT5 survival (RNA) · tumor vs normal (RNA) · all KRT5 data types