KRT40

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRT40 mutation is significantly associated with the RNA expression of many other genes, with 1,247 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT40-associated genes across cancer lineages are CASTOR2, MTA3P1, and RN7SL456P. Each is linked with KRT40 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT40-to-partner and partner-to-KRT40 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT40→partner) and Y-score (partner→KRT40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCASTOR2 →+0.829+3.708<.001<.00132
LIHCMTA3P1 →+0.026+4.878<.001.00532
LIHCRN7SL456P →+0.099+5.305.007.00332
UCECSEC13 →+0.427+3.848<.001<.00132
UCECRRM1 →+0.785+2.606<.001.00532
COADKIR3DL1 →+0.220+3.652.006.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,247 associations by consensus.

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