Across TCGA cell cohorts, KRT40 RNA expression is significantly associated with the go_rna of many other GO terms, with 779 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KRT40-associated GO terms across cancer lineages are Negative regulation of potassium ion transmembrane transporter activity, Negative regulation of voltage-gated potassium channel activity, and Positive regulation of striated muscle contraction. Each is linked with KRT40 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT40-to-partner and partner-to-KRT40 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT40→partner) and Y-score (partner→KRT40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of potassium ion transmembrane transporter activity →	+1.164	+0.255	<.001	.006	3	4
BREAST	Negative regulation of voltage-gated potassium channel activity →	+1.164	+0.255	<.001	.006	3	4
LUNG_NSCLC_LUAD	Positive regulation of striated muscle contraction →	-0.133	-0.092	.001	.002	3	4
BREAST	Layer formation in cerebral cortex →	+0.100	+0.195	.001	.008	3	4
LUNG_SCLC	Positive regulation of lipid localization →	-0.094	-2.578	.003	.007	3	4
LUNG_SCLC	Regulation of sterol transport →	-0.070	-2.152	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 779 associations by consensus.

Exploration

KRT40 survival (RNA) · tumor vs normal (RNA) · all KRT40 data types