KRT36

Across TCGA patient cohorts, KRT36 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,018 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KRT36-associated GO terms across cancer lineages are Regulation of alpha-beta T cell activation, B cell homeostasis, and Positive regulation of interleukin-12 production. Each is linked with KRT36 in more than 23 cancer types. Because this analysis shows association rather than direction, both KRT36-to-partner and partner-to-KRT36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of alpha-beta T cell activation grouped by KRT36-low versus KRT36-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT36→partner) and Y-score (partner→KRT36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Regulation of alpha-beta T cell activation →	+0.096	+0.204	<.001	<.001	3	24
SCLC	B cell homeostasis →	+0.082	+0.162	<.001	<.001	3	23
SCLC	Positive regulation of interleukin-12 production →	+0.113	+0.240	<.001	<.001	3	23
SCLC	Regulation of lymphocyte differentiation →	+0.085	+0.213	<.001	<.001	3	23
SCLC	Negative regulation of immune response →	+0.087	+0.167	<.001	<.001	3	23
SCLC	Regulation of leukocyte proliferation →	+0.103	+0.214	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,018 associations by consensus.

Regulation of alpha-beta T cell activation by KRT36 expression — SCLC

Explore this box plot interactively →