KRT36

Across TCGA cell cohorts, KRT36 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRT36-associated genes across cancer lineages are OR1E2, OR8B12, and OR8A1. Each is linked with KRT36 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT36-to-partner and partner-to-KRT36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1E2 grouped by KRT36-low versus KRT36-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT36→partner) and Y-score (partner→KRT36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR1E2 →	+0.016	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR8B12 →	+0.073	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR8A1 →	+0.576	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR8B8 →	+0.019	+4.734	.004	.002	3	1
LUNG_NSCLC_LUAD	OR10D3 →	+0.137	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	POM121L12 →	+0.022	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR1E2 by KRT36 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →