KRT36

Across TCGA cell cohorts, KRT36 mutation is significantly associated with the mutation status of many other genes, with 1,511 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT36-associated genes across cancer lineages are RICTOR, ECPAS, and ABCA8. Each is linked with KRT36 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT36-to-partner and partner-to-KRT36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RICTOR grouped by KRT36-low versus KRT36-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT36→partner) and Y-score (partner→KRT36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	RICTOR →	+5.000	+4.187	.008	.008	1	4
LUNG_NSCLC_LUAD	ECPAS →	+3.584	+4.063	.003	.003	1	3
LUNG_NSCLC_LUAD	ABCA8 →	+3.000	+3.662	.007	.007	1	3
LUNG_NSCLC_LUAD	FBLN2 →	+2.830	+4.469	.001	.001	1	3
LUNG_NSCLC_LUAD	SH3TC2 →	+4.000	+4.303	.001	.001	1	3
LUNG_NSCLC_LUAD	VWC2 →	+3.584	+4.063	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,511 associations by consensus.

RICTOR by KRT36 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →