Across TCGA patient cohorts, KRT35 mutation is significantly associated with the RNA expression of many other genes, with 996 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT35-associated genes across cancer lineages are RPL22P14, LINC02380, and RNA5SP412. Each is linked with KRT35 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT35-to-partner and partner-to-KRT35 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT35→partner) and Y-score (partner→KRT35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPL22P14 →	+0.146	+3.376	<.001	.008	3	3
LUAD	LINC02380 →	+0.129	+4.160	<.001	<.001	3	3
UCEC	RNA5SP412 →	+0.722	+2.604	<.001	<.001	3	3
LIHC	RPL12P48 →	+0.114	+5.033	<.001	.009	3	2
LIHC	LINC02339 →	+0.052	+6.902	<.001	<.001	3	2
READ	MIRLET7F1 →	+0.486	+4.533	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 996 associations by consensus.

Exploration

KRT35 survival (RNA) · tumor vs normal (RNA) · all KRT35 data types