Across TCGA cell cohorts, KRT35 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KRT35-associated genes across cancer lineages are OR8B12, OR8A1, and OR8B2. Each is linked with KRT35 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT35-to-partner and partner-to-KRT35 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT35→partner) and Y-score (partner→KRT35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR8B12 →	+0.030	+4.369	<.001	.008	3	2
SOFT_TISSUE	OR8A1 →	+0.504	+4.417	<.001	.004	3	2
SOFT_TISSUE	OR8B2 →	+0.036	+4.369	<.001	.008	3	2
BLOOD_Leukemia	C1orf94 →	+0.054	+4.152	<.001	.009	3	2
SOFT_TISSUE	H2BC1 →	+0.325	+4.977	<.001	.002	3	1
SOFT_TISSUE	H2AC1 →	+0.145	+4.977	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

KRT35 survival (RNA) · tumor vs normal (RNA) · all KRT35 data types