KRT33B

Across TCGA patient cohorts, KRT33B mutation is significantly associated with the RNA expression of many other genes, with 2,949 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT33B-associated genes across cancer lineages are RN7SL26P, PKN3, and RECQL4. Each is linked with KRT33B in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT33B-to-partner and partner-to-KRT33B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL26P grouped by KRT33B-low versus KRT33B-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT33B→partner) and Y-score (partner→KRT33B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RN7SL26P →	+0.282	+2.969	.009	.006	3	4
UCEC	PKN3 →	+0.736	+2.069	<.001	<.001	3	3
UCEC	RECQL4 →	+0.541	+3.700	.002	.001	3	3
UCEC	MFSD12 →	+0.480	+2.787	<.001	<.001	3	3
UCEC	PAQR4 →	+0.523	+2.338	.006	.003	3	3
UCEC	POC1A →	+0.535	+3.264	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,949 associations by consensus.

RN7SL26P by KRT33B expression — STAD

Explore this box plot interactively →