KRT31

Across TCGA cell cohorts, KRT31 mutation is significantly associated with the drug of many other genes, with 52 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT31-associated genes across cancer lineages are Axitinib, LMP744, and Bosutinib. Each is linked with KRT31 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT31-to-partner and partner-to-KRT31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Axitinib grouped by KRT31-low versus KRT31-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT31→partner) and Y-score (partner→KRT31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Axitinib →	+0.574	+2.807	.035	.046	3	2
LARGE_INTESTINE	LMP744 →	+0.786	+2.710	.019	.027	3	2
LARGE_INTESTINE	Bosutinib →	+0.525	+2.700	.002	.030	3	1
LARGE_INTESTINE	Tanespimycin →	+0.496	+2.807	.045	.046	3	1
LARGE_INTESTINE	AZD8055 →	+0.516	+2.807	.032	.046	3	1
LARGE_INTESTINE	I-BET-762 →	+0.577	+2.868	.011	.022	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Axitinib by KRT31 expression — LARGE_INTESTINE

Explore this box plot interactively →