Across TCGA pan-cancer cohorts, KRT26 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KRT26’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where KRT26 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT26 is over-expressed in tumor.

KIRP and LUSC are the cancer types where KRT26 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT26 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	All	+0.040	.046	1	view →
LUSC	Male	II,III,IV	+0.012	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: KRT26 RNA expression & survival · all KRT26 data types