KRT20

Across TCGA pan-cancer cohorts, KRT20 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KRT20 data layer compared with 17 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher KRT20 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KRT20 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where KRT20 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.913	.014	54	view →
PDAC	OS	Quartile	II,III,IV	0.708	0.393	<.001	38	view →
LUAD	OS	Quartile	All	0.548	0.936	.011	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KRT20–COAD (DFS)

Open the COAD breakdown →