KRT2

Across TCGA cell cohorts, KRT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 793 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRT2-associated GO terms across cancer lineages are Response to thyroxine, Myeloid cell apoptotic process, and Response to L-phenylalanine derivative. Each is linked with KRT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KRT2-to-partner and partner-to-KRT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to thyroxine grouped by KRT2-low versus KRT2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT2→partner) and Y-score (partner→KRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Response to thyroxine →	+0.098	+0.106	.004	.001	3	4
BLOOD_Leukemia	Myeloid cell apoptotic process →	+0.079	+0.372	<.001	.002	3	4
LUNG_NSCLC_LUAD	Response to L-phenylalanine derivative →	+0.084	+0.076	.006	.009	3	4
LUNG_NSCLC_LUAD	Positive regulation of intrinsic apoptotic signaling pathway →	+0.063	+0.086	.002	.003	3	4
LUNG_NSCLC_LUAD	Cellular response to jasmonic acid stimulus →	+0.800	+0.104	.008	.005	3	3
LUNG_NSCLC_LUAD	Response to jasmonic acid →	+0.800	+0.104	.008	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 793 associations by consensus.

Response to thyroxine by KRT2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →