KRT19

Across TCGA patient cohorts, KRT19 mutation is significantly associated with the RNA expression of many other genes, with 1,261 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT19-associated genes across cancer lineages are KIAA1841, SNX11, and SARM1. Each is linked with KRT19 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT19-to-partner and partner-to-KRT19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIAA1841 grouped by KRT19-low versus KRT19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT19→partner) and Y-score (partner→KRT19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIAA1841 →	+0.456	+2.906	.007	.002	3	2
UCEC	SNX11 →	+0.383	+4.053	.001	<.001	3	2
UCEC	SARM1 →	+0.484	+3.202	<.001	.009	3	2
UCEC	NSF →	+0.580	+3.716	.001	<.001	3	2
UCEC	DLG3 →	+0.513	+3.475	.002	.002	3	2
UCEC	RFFL →	+0.563	+2.243	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,261 associations by consensus.

KIAA1841 by KRT19 expression — UCEC

Explore this box plot interactively →