KRT19

Across TCGA cell cohorts, KRT19 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,560 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRT19-associated GO terms across cancer lineages are Negative regulation of actin filament polymerization, Negative regulation of supramolecular fiber organization, and Negative regulation of protein-containing complex assembly. Each is linked with KRT19 in more than 11 cancer types. Because this analysis shows association rather than direction, both KRT19-to-partner and partner-to-KRT19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of actin filament polymerization grouped by KRT19-low versus KRT19-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT19→partner) and Y-score (partner→KRT19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of actin filament polymerization →	+0.175	+2.301	<.001	<.001	3	12
STOMACH	Negative regulation of supramolecular fiber organization →	+0.086	+4.209	<.001	<.001	3	11
BONE	Negative regulation of protein-containing complex assembly →	+0.077	+1.522	<.001	<.001	3	11
LARGE_INTESTINE	Vacuolar transport →	+0.060	+2.571	<.001	.001	3	11
LUNG_NSCLC_LUSC	Myofibril assembly →	+0.216	+3.971	<.001	<.001	3	10
URINARY_TRACT	Negative regulation of protein polymerization →	+0.147	+3.544	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,560 associations by consensus.

Negative regulation of actin filament polymerization by KRT19 expression — PANCREAS

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