KRT19

Across TCGA cell cohorts, KRT19 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KRT19-associated genes across cancer lineages are TBL1Y, TXNDC8, and SH3GL2. Each is linked with KRT19 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT19-to-partner and partner-to-KRT19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBL1Y grouped by KRT19-low versus KRT19-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT19→partner) and Y-score (partner→KRT19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TBL1Y →	+0.053	+4.643	<.001	.008	3	1
URINARY_TRACT	TXNDC8 →	+0.013	+5.087	<.001	.004	3	1
LARGE_INTESTINE	SH3GL2 →	+1.751	+3.474	<.001	.003	3	1
LARGE_INTESTINE	ACADL →	+0.749	+3.404	<.001	.006	3	1
LARGE_INTESTINE	A4GNT →	+0.070	+3.392	<.001	<.001	3	1
LARGE_INTESTINE	GALR3 →	+0.081	+3.424	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TBL1Y by KRT19 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →