Across TCGA pan-cancer cohorts, KRT18P9 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of KRT18P9’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where KRT18P9 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT18P9 is over-expressed in tumor, although a few such as READ show the opposite, repressed pattern.
COAD, BRCA, and READ are the cancer types where KRT18P9 tumor–normal differential expression is most reproducible.