KRT18P63

Across TCGA pan-cancer cohorts, KRT18P63 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated KRT18P63 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher KRT18P63 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT18P63 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LAML show a favorable association.

ACC, HNSC, and MESO are the cancer types where KRT18P63 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.245	0.712	<.001	62	view →
HNSC	DFS	Quartile	All	0.805	0.643	.001	47	view →
MESO	OS	Tertile	All	0.374	0.609	.005	32	view →
LAML	DFS	Tertile	All	0.604	0.262	.011	22	view →
UCS	DFS	Tertile	IV	0.975	0.484	.024	22	view →
STAD	DFS	Median	IV	0.148	0.726	<.001	21	view →
SKCM	DFS	Tertile	All	0.660	0.533	.030	12	view →
READ	DFS	Median	IV	0.349	0.839	.003	12	view →
UVM	DFS	Tertile	All	0.757	0.531	.028	11	view →
LIHC	DFS	Quartile	All	0.195	0.455	.009	10	view →
SARC	DFS	Tertile	All	0.245	0.450	.031	7	view →
ESCA	OS	Tertile	IV	0.243	0.743	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

KRT18P63–ACC (DFS)

Open the ACC breakdown →